The developers of iVOC published a scientific paper with the European Journal of Orthodontics titled (Reminders improve oral hygiene and adherence to appointments in orthodontic patients: a systematic review and meta-analysis). They concluded that “There is moderate-to-high quality of evidence that reminders have a positive effect on OH and adherence to appointments in orthodontic patients. These effects were demonstrated in the short- and long-term. Future high-quality RCTs should be designed with longer follow-up periods. There are several other published papers in this fields.